Host cell factor C1

HCFC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4GO6, 4N39, 4N3A, 4N3B, 4N3C
Identifiers
Aliases	HCFC1, CFF, HCF-1, HCF1, HFC1, MRX3, PPP1R89, VCAF, HCF, Host cell factor C1, XLID3, MAHCX
External IDs	OMIM: 300019; MGI: 105942; HomoloGene: 3898; GeneCards: HCFC1; OMA:HCFC1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	153,971,818 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	73,009,963 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; parotid gland; ; Skeletal muscle tissue of rectus abdominis; ; ganglionic eminence; ; anterior pituitary; ; nipple; ; ventricular zone; ; body of uterus; ; pylorus; ; apex of heart;
	Top expressed in
	genital tubercle; ; tail of embryo; ; epiblast; ; ventricular zone; ; mandibular prominence; ; thymus; ; ganglionic eminence; ; fetal liver hematopoietic progenitor cell; ; maxillary prominence; ; somite;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; transcription coactivator activity; chromatin binding; histone acetyltransferase activity (H4-K8 specific); histone acetyltransferase activity (H4-K5 specific); DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; identical protein binding; histone acetyltransferase activity (H4-K16 specific); cadherin binding; protein-macromolecule adaptor activity; sequence-specific double-stranded DNA binding;
Cellular component	cytoplasm; membrane; SAGA-type complex; Set1C/COMPASS complex; axon; soma; MLL1 complex; dendrite; histone acetyltransferase complex; nucleus; nucleoplasm; protein-containing complex;
Biological process	regulation of transcription, DNA-templated; release from viral latency; cellular response to organic cyclic compound; protein stabilization; mitochondrion organization; negative regulation of transcription by RNA polymerase II; histone H4-K5 acetylation; positive regulation of gene expression; positive regulation of cell cycle; cell cycle; histone H4-K16 acetylation; viral process; histone H4-K8 acetylation; regulation of protein-containing complex assembly; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; protein deubiquitination; blastocyst hatching; chromatin organization; positive regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	3054
	15161
	ENSG00000172534
	ENSMUSG00000031386
	P51610
	Q61191
	NM_005334
	NM_008224
	NP_005325
	NP_032250
	Wikidata
View/Edit Human	View/Edit Mouse

Host cell factor 1 (HCFC1, HCF1, or HCF-1), also known as VP16-accessory protein, is a protein that in humans is encoded by the HCFC1 gene.