HCN2

HCN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MPF, 3U10
Identifiers
Aliases	HCN2, BCNG-2, BCNG2, HAC-1, hyperpolarization activated cyclic nucleotide gated potassium channel 2, hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2, EIG17, FEB2, GEFSP11
External IDs	OMIM: 602781; MGI: 1298210; HomoloGene: 31022; GeneCards: HCN2; OMA:HCN2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	617,159 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	79,571,942 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; right frontal lobe; ; putamen; ; nucleus accumbens; ; anterior cingulate cortex; ; caudate nucleus; ; Brodmann area 10; ; Brodmann area 9; ; Amygdala; ; right hemisphere of cerebellum;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; primary visual cortex; ; superior frontal gyrus; ; CA3 field; ; choroid plexus of fourth ventricle; ; central gray substance of midbrain; ; cerebellar cortex; ; Medulla Oblongata; ; lumbar subsegment of spinal cord;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; potassium channel activity; cAMP binding; sodium channel activity; voltage-gated ion channel activity; ion channel activity; intracellular cAMP-activated cation channel activity; identical protein binding; voltage-gated potassium channel activity; voltage-gated sodium channel activity; protein binding;
Cellular component	integral component of membrane; membrane; voltage-gated potassium channel complex; plasma membrane; integral component of plasma membrane; HCN channel complex;
Biological process	cellular response to cGMP; sodium ion transmembrane transport; sodium ion transport; cell-cell signaling; regulation of membrane potential; regulation of ion transmembrane transport; ion transport; potassium ion transport; transmembrane transport; potassium ion transmembrane transport; cellular response to cAMP; membrane depolarization during cardiac muscle cell action potential; sodium ion import across plasma membrane; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	610
	15166
	ENSG00000099822
	ENSMUSG00000020331
	Q9UL51
	O88703
	NM_001194
	NM_008226
	NP_001185
	NP_032252
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 is a protein that in humans is encoded by the HCN2 gene.