HDAC7

HDAC7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3C0Y, 3C0Z, 3C10, 3ZNR, 3ZNS
Identifiers
Aliases	HDAC7, HD7A, HDAC7A, HD7, histone deacetylase 7
External IDs	OMIM: 606542; MGI: 1891835; HomoloGene: 9124; GeneCards: HDAC7; OMA:HDAC7 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	47,833,132 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	97,742,383 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; gastric mucosa; ; left uterine tube; ; body of uterus; ; apex of heart; ; upper lobe of left lung; ; left adrenal cortex; ; canal of the cervix; ; right ovary; ; right uterine tube;
	Top expressed in
	thymus; ; genital tubercle; ; corneal stroma; ; otic vesicle; ; entorhinal cortex; ; perirhinal cortex; ; lactiferous gland; ; ascending aorta; ; aortic valve; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; transcription corepressor activity; protein kinase binding; 14-3-3 protein binding; hydrolase activity; protein kinase C binding; chromatin binding; histone deacetylase activity; NAD-dependent histone deacetylase activity (H3-K14 specific); protein binding; SUMO transferase activity;
Cellular component	nucleoplasm; cytoplasm; nucleus; histone deacetylase complex; cytosol;
Biological process	transcription, DNA-templated; negative regulation of NIK/NF-kappaB signaling; positive regulation of cell migration involved in sprouting angiogenesis; cell-cell junction assembly; vasculogenesis; negative regulation of transcription by RNA polymerase II; histone H3 deacetylation; negative regulation of osteoblast differentiation; negative regulation of interleukin-2 production; regulation of transcription, DNA-templated; histone deacetylation; negative regulation of transcription, DNA-templated; chromatin organization; protein sumoylation;
	Sources:Amigo / QuickGO
Orthologs
	51564
	56233
	ENSG00000061273
	ENSMUSG00000022475
	Q8WUI4
	Q8C2B3
	NM_001098416; NM_001308090; NM_015401; NM_016596; NM_001368046
NM_001204275; NM_001204276; NM_001204277; NM_001204278; NM_001204279;
	NM_001204280; NM_001204281; NM_019572; NM_001378971
	NP_001091886; NP_001295019; NP_056216; NP_001354975
NP_001191204; NP_001191205; NP_001191206; NP_001191207; NP_001191208;
	NP_001191209; NP_001191210; NP_062518; NP_001365900
	Wikidata
View/Edit Human	View/Edit Mouse

Histone deacetylase 7 is an enzyme that in humans is encoded by the HDAC7 gene.