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| HEPACAM |
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| Identifiers |
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| Aliases | HEPACAM, GlialCAM, MLC2A, MLC2B, hepatic and glial cell adhesion molecule, HEPACAM1, HEPN1 |
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| External IDs | OMIM: 611642; MGI: 1920177; HomoloGene: 17652; GeneCards: HEPACAM; OMA:HEPACAM - orthologs |
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| Gene location (Mouse) |
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| | Chr. | Chromosome 9 (mouse) |
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| | Band | 9|9 A4 | Start | 37,278,647 bp |
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| End | 37,297,871 bp |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - external globus pallidus
- pars reticulata
- internal globus pallidus
- entorhinal cortex
- caudate nucleus
- pars compacta
- lateral nuclear group of thalamus
- postcentral gyrus
- Amygdala
- primary visual cortex
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| | Top expressed in | - lumbar subsegment of spinal cord
- deep cerebellar nuclei
- cerebellar cortex
- suprachiasmatic nucleus
- globus pallidus
- primary visual cortex
- central gray substance of midbrain
- otolith organ
- lateral geniculate nucleus
- utricle
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| | More reference expression data |
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| BioGPS | |
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| Wikidata |
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Gene HEPACAM*, named based on its original site of identification - hepatocytes and the nature of its protein product - a cell adhesion molecule (CAM), was first discovered and characterised in human liver. The gene encodes a protein of 416 amino acids, designated as hepaCAM**, which is a new member of the immunoglobulin superfamily of cell adhesion molecules (IgSF CAM). The main biological functions of hepaCAM include a) modulating cell-matrix adhesion and migration, and b) inhibiting cancer cell growth.
(Note: *HEPACAM, gene name; **hepaCAM, protein name)
