Hes family bhlh transcription factor 2

HES2
Identifiers
Aliases	HES2, bHLHb40, hes family bHLH transcription factor 2
External IDs	OMIM: 609970; MGI: 1098624; HomoloGene: 22455; GeneCards: HES2; OMA:HES2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	6,424,670 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	152,246,926 bp
RNA expression pattern
	Top expressed in
	mucosa of esophagus; ; mucosa of transverse colon; ; buccal mucosa cell; ; placenta; ; skin of abdomen; ; gingival epithelium; ; skin of leg; ; vagina; ; right uterine tube; ; olfactory zone of nasal mucosa;
	Top expressed in
	embryo; ; lip; ; jejunum; ; right kidney; ; proximal tubule; ; duodenum; ; yolk sac; ; Ileal epithelium; ; esophagus; ; lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; double-stranded DNA binding; transcription factor binding; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; transcription corepressor activity; sequence-specific DNA binding; sequence-specific double-stranded DNA binding;
Cellular component	nucleus;
Biological process	negative regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; somitogenesis; Notch signaling pathway; cell differentiation; regulation of neurogenesis; anterior/posterior pattern specification;
	Sources:Amigo / QuickGO
Orthologs
	54626
	15206
	ENSG00000069812
	ENSMUSG00000028940
	Q9Y543
	O54792
	NM_019089
	NM_001301805; NM_008236
	NP_061962
	NP_001288734; NP_032262
	Wikidata
View/Edit Human	View/Edit Mouse

Hes family bHLH transcription factor 2 is a protein that in humans is encoded by the HES2 gene.