HES6

HES6
Identifiers
Aliases	HES6, C-HAIRY1, HES-6, bHLHb41, bHLHc23, hes family bHLH transcription factor 6
External IDs	OMIM: 610331; MGI: 1859852; HomoloGene: 23111; GeneCards: HES6; OMA:HES6 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	238,240,662 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	91,341,760 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; secondary oocyte; ; C1 segment; ; mucosa of transverse colon; ; anterior pituitary; ; Brodmann area 9; ; primary visual cortex; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	ventricular zone; ; fossa; ; right kidney; ; internal carotid artery; ; adrenal gland; ; saccule; ; ganglionic eminence; ; left lobe of liver; ; Paneth cell; ; proximal tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; transcription factor binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein dimerization activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; transcription coregulator activity; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription corepressor activity; sequence-specific DNA binding; sequence-specific double-stranded DNA binding;
Cellular component	nucleus; transcription regulator complex;
Biological process	regulation of transcription by RNA polymerase II; multicellular organism development; cell differentiation; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; nervous system development; regulation of transcription, DNA-templated; somitogenesis; Notch signaling pathway; regulation of neurogenesis; anterior/posterior pattern specification;
	Sources:Amigo / QuickGO
Orthologs
	55502
	55927
	ENSG00000144485
	ENSMUSG00000067071
	Q96HZ4
	Q9JHE6
	NM_018645; NM_001142853; NM_001282434
	NM_019479; NM_001360899; NM_001360900
	NP_001136325; NP_001269363; NP_061115
	NP_062352; NP_001347828; NP_001347829
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene.