HHIPL1

HHIPL1
Identifiers
Aliases	HHIPL1, KIAA1822, UNQ9245, HHIP like 1
External IDs	MGI: 1919265; HomoloGene: 81985; GeneCards: HHIPL1; OMA:HHIPL1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	99,680,569 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	108,297,128 bp
RNA expression pattern
	Top expressed in
	caudate nucleus; ; cingulate gyrus; ; anterior cingulate cortex; ; putamen; ; right frontal lobe; ; ventricular zone; ; Amygdala; ; nucleus accumbens; ; prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	decidua; ; stroma of bone marrow; ; gastrula; ; lumbar subsegment of spinal cord; ; ventricular zone; ; uterus; ; visual cortex; ; superior frontal gyrus; ; facial motor nucleus; ; lateral hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	scavenger receptor activity; catalytic activity; molecular function;
Cellular component	extracellular region; membrane; cellular component;
Biological process	receptor-mediated endocytosis; biological process; vesicle-mediated transport; endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	84439
	214305
	ENSG00000182218
	ENSMUSG00000021260
	Q96JK4
	Q14DK5
	NM_001127258; NM_032425; NM_001329411
	NM_001044380
	NP_001120730; NP_001316340; NP_115801
	NP_001037845
	Wikidata
View/Edit Human	View/Edit Mouse

HHIP-like protein 1 (HHIPL1), also known as HHIP2, is a protein that in humans is encoded by the HHIPL1 gene on chromosome 14. It is not significantly expressed in many tissues and cell types, though HHIPL1 mRNA has been detected in trabecular bone cells. Little is known about the precise biological function of HHIPL1, but the protein has been linked to adenomas. The HHIPL1 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.