HIC1

HIC1
Identifiers
Aliases	HIC1, ZBTB29, ZNF901, hic-1, hypermethylated in cancer 1, HIC ZBTB transcriptional repressor 1
External IDs	OMIM: 603825; MGI: 1338010; HomoloGene: 4740; GeneCards: HIC1; OMA:HIC1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	2,063,241 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	75,060,345 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; stromal cell of endometrium; ; apex of heart; ; sural nerve; ; vena cava; ; right ovary; ; left ovary; ; left uterine tube; ; body of uterus; ; pericardium;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; vas deferens; ; efferent ductule; ; Gonadal ridge; ; female urethra; ; dermis; ; placenta; ; gastrula; ; uterus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; histone deacetylase binding; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	chromatin; nucleus; cytosol; nucleoplasm;
Biological process	multicellular organism development; negative regulation of Wnt signaling pathway; positive regulation of DNA damage response, signal transduction by p53 class mediator; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; Wnt signaling pathway; transcription, DNA-templated; intrinsic apoptotic signaling pathway in response to DNA damage; cellular response to DNA damage stimulus;
	Sources:Amigo / QuickGO
Orthologs
	3090
	15248
	ENSG00000177374
	ENSMUSG00000043099
	Q14526
	Q9R1Y5
	NM_006497; NM_001098202
	NM_001098203; NM_010430
	NP_001091672; NP_006488
	NP_001091673; NP_034560
	Wikidata
View/Edit Human	View/Edit Mouse

Hypermethylated in cancer 1 protein is a protein that in humans is encoded by the HIC1 gene.