HIKESHI

HIKESHI
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3WVZ, 3WW0
Identifiers
Aliases	HIKESHI, HSPC179, Hikeshi, L7RN6, OPI10, HSPC138, C11orf73, HLD13, chromosome 11 open reading frame 73, Hikeshi, heat shock protein nuclear import factor, heat shock protein nuclear import factor hikeshi
External IDs	OMIM: 614908; MGI: 96738; HomoloGene: 6908; GeneCards: HIKESHI; OMA:HIKESHI - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	86,345,943 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	89,590,412 bp
RNA expression pattern
	Top expressed in
	myocardium of left ventricle; ; tibialis anterior muscle; ; cardiac muscle tissue of right atrium; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; deltoid muscle; ; upper arm; ; biceps brachii; ; skin of arm; ; muscle of thigh;
	Top expressed in
	medial ganglionic eminence; ; embryo; ; triceps brachii muscle; ; sternocleidomastoid muscle; ; blastocyst; ; muscle of thigh; ; temporal muscle; ; morula; ; morula; ; digastric muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	Hsp70 protein binding; nuclear import signal receptor activity;
Cellular component	cytoplasm; cytosol; intracellular anatomical structure; nucleus; nucleoplasm;
Biological process	protein transport; regulation of cellular response to heat; protein import into nucleus; cellular response to heat; Golgi organization; lung development;
	Sources:Amigo / QuickGO
Orthologs
	51501
	67669
	ENSG00000149196
	ENSMUSG00000062797
	Q53FT3
	Q9DD02
	NM_016401; NM_001322404; NM_001322407; NM_001322409
	NM_001291286; NM_001291287; NM_001291288; NM_001291289; NM_026304
	NP_001309333; NP_001309336; NP_001309338; NP_057485
	NP_001278215; NP_001278216; NP_001278217; NP_001278218; NP_080580
	Wikidata
View/Edit Human	View/Edit Mouse

HIKESHI is a protein important in lung and multicellular organismal development that, in humans, is encoded by the HIKESHI gene. HIKESHI is found on chromosome 11 in humans and chromosome 7 in mice. Similar sequences (orthologs) are found in most opisthokonts. The mouse homolog, lethal gene on chromosome 7 Rinchik 6 protein is encoded by the l7Rn6 gene (renamed to Hikeshi after the harmonization of human and mouse gene names).