HINT2

HINT2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4INC, 4INI, 4NJX, 4NJY, 4NJZ, 4NK0
Identifiers
Aliases	HINT2, HIT-17, histidine triad nucleotide binding protein 2
External IDs	OMIM: 609997; MGI: 1916167; HomoloGene: 13072; GeneCards: HINT2; OMA:HINT2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	35,815,354 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	43,656,466 bp
RNA expression pattern
	Top expressed in
	apex of heart; ; right lobe of liver; ; right adrenal gland; ; right adrenal cortex; ; left adrenal cortex; ; human kidney; ; muscle of thigh; ; left ventricle; ; mucosa of transverse colon; ; olfactory zone of nasal mucosa;
	Top expressed in
	right kidney; ; choroid plexus of fourth ventricle; ; left lobe of liver; ; Ileal epithelium; ; human kidney; ; proximal tubule; ; interventricular septum; ; right ventricle; ; myocardium of ventricle; ; yolk sac;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; catalytic activity; hydrolase activity;
Cellular component	nucleolus; mitochondrion;
Biological process	steroid biosynthetic process; lipid metabolism; apoptotic process; negative regulation of peptidyl-lysine acetylation; lipid catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	84681
	68917
	ENSG00000137133
	ENSMUSG00000028470
	Q9BX68
	Q9D0S9
	NM_032593
	NM_026871
	NP_115982
	NP_081147
	Wikidata
View/Edit Human	View/Edit Mouse

Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein that in humans is encoded by the HINT2 gene on chromosome 9. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression.