HIP1R

HIP1R
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1R0D
Identifiers
Aliases	HIP1R, HIP12, HIP3, ILWEQ, huntingtin interacting protein 1 related
External IDs	OMIM: 605613; MGI: 1352504; HomoloGene: 78348; GeneCards: HIP1R; OMA:HIP1R - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	122,862,961 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	124,143,621 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; inferior olivary nucleus; ; skin of leg; ; right frontal lobe; ; body of pancreas; ; Amygdala; ; skin of abdomen; ; anterior pituitary; ; dorsal motor nucleus of vagus nerve; ; Hypothalamus;
	Top expressed in
	transitional epithelium of urinary bladder; ; saccule; ; epithelium of stomach; ; granulocyte; ; otic placode; ; otic vesicle; ; hair follicle; ; lip; ; submandibular gland; ; motor neuron;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	actin binding; protein binding; phospholipid binding; phosphatidylinositol binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-3,4,5-trisphosphate binding; SH3 domain binding; clathrin binding; clathrin light chain binding; clathrin adaptor activity; protein homodimerization activity; phosphatidylinositol-3,4-bisphosphate binding; protein heterodimerization activity; actin filament binding; phosphatidylinositol-3,5-bisphosphate binding; identical protein binding;
Cellular component	perinuclear region of cytoplasm; clathrin-coated pit; cytoskeleton; clathrin-coated vesicle membrane; intracellular membrane-bounded organelle; endomembrane system; membrane; cytoplasmic vesicle; clathrin-coated vesicle; cytoplasm; mitochondrion; cytosol; cell cortex; postsynaptic density; apical plasma membrane; ruffle membrane; dendrite cytoplasm; soma; dendritic spine; synaptic membrane; AP-2 adaptor complex; actin cortical patch;
Biological process	endocytosis; receptor-mediated endocytosis; apoptotic process; activation of cysteine-type endopeptidase activity involved in apoptotic process; regulation of endocytosis; negative regulation of actin filament polymerization; positive regulation of protein binding; regulation of actin cytoskeleton organization; negative regulation of Arp2/3 complex-mediated actin nucleation; positive regulation of apoptotic process; negative regulation of apoptotic process; positive regulation of epidermal growth factor receptor signaling pathway; clathrin coat assembly; protein stabilization; digestive system development; regulation of gastric acid secretion; membrane organization; positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway; positive regulation of clathrin coat assembly; positive regulation of platelet-derived growth factor receptor-beta signaling pathway; regulation of clathrin-dependent endocytosis; actin filament organization; positive regulation of receptor-mediated endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	9026
	29816
	ENSG00000130787
	ENSMUSG00000000915
	O75146
	Q9JKY5
	NM_001303097; NM_001303099; NM_003959
	NM_145070
	NP_001290026; NP_001290028; NP_003950
	NP_659507
	Wikidata
View/Edit Human	View/Edit Mouse

Huntingtin-interacting protein 1-related protein is a protein that in humans is encoded by the HIP1R gene.