HIPK1

HIPK1
Identifiers
Aliases	HIPK1, Myak, Nbak2, homeodomain interacting protein kinase 1
External IDs	OMIM: 608003; MGI: 1314873; HomoloGene: 56483; GeneCards: HIPK1; OMA:HIPK1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	113,977,869 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	103,698,879 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; cerebellar vermis; ; mucosa of paranasal sinus; ; paraflocculus of cerebellum; ; Epithelium of choroid plexus; ; caput epididymis; ; buccal mucosa cell; ; thymus; ; bone marrow; ; trabecular bone;
	Top expressed in
	vestibular membrane of cochlear duct; ; blood; ; tibiofemoral joint; ; fetal liver hematopoietic progenitor cell; ; granulocyte; ; genital tubercle; ; gastrula; ; stroma of bone marrow; ; right lung; ; submandibular gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding;
Cellular component	cytoplasm; PML body; nuclear speck; nucleus; nucleoplasm; centrosome; cytosol;
Biological process	eye development; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; regulation of transcription, DNA-templated; retina layer formation; extrinsic apoptotic signaling pathway; adherens junction assembly; phosphorylation; iris morphogenesis; regulation of tumor necrosis factor-mediated signaling pathway; transcription, DNA-templated; positive regulation of angiogenesis; protein phosphorylation; embryonic camera-type eye morphogenesis; lens induction in camera-type eye; neuron differentiation; positive regulation of cell population proliferation; embryonic retina morphogenesis in camera-type eye; definitive hemopoiesis; smoothened signaling pathway; endothelial cell apoptotic process; anterior/posterior pattern specification; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	204851
	15257
	ENSG00000163349
	ENSMUSG00000008730
	Q86Z02
	O88904
NM_152696; NM_181358; NM_198268; NM_198269; NM_001369806;
	NM_001369807
	NM_001301304; NM_001301306; NM_010432
NP_689909; NP_852003; NP_938009; NP_938010; NP_001356735;
	NP_001356736
	NP_001288233; NP_001288235; NP_034562
	Wikidata
View/Edit Human	View/Edit Mouse

Homeodomain-interacting protein kinase 1 is an enzyme that, in humans is encoded by the HIPK1 gene.