HIVEP1

HIVEP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1BBO, 4ZNF
Identifiers
Aliases	HIVEP1, CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A, human immunodeficiency virus type I enhancer binding protein 1, HIVEP zinc finger 1
External IDs	OMIM: 194540; MGI: 96100; HomoloGene: 1596; GeneCards: HIVEP1; OMA:HIVEP1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	12,164,999 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	42,346,013 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; cartilage tissue; ; sural nerve; ; epithelium of colon; ; superficial temporal artery; ; jejunal mucosa; ; seminal vesicula; ; oral cavity; ; right lobe of liver; ; caput epididymis;
	Top expressed in
	zygote; ; genital tubercle; ; secondary oocyte; ; primary oocyte; ; tail of embryo; ; medial dorsal nucleus; ; lateral geniculate nucleus; ; primary motor cortex; ; habenula; ; medial geniculate nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA binding; sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; mitochondrion; nucleus; nucleoplasm; nuclear body;
Biological process	multicellular organism development; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; signal transduction; transcription, DNA-templated; BMP signaling pathway; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3096
	110521
	ENSG00000095951
	ENSMUSG00000021366
	P15822
	Q03172
	NM_002114
	NM_007772
	NP_002105
	NP_031798
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 40 is a protein that in humans is encoded by the HIVEP1 gene.

Members of the ZAS family, such as ZAS1 (HIVEP1), are large proteins that contain a ZAS domain, a modular protein structure consisting of a pair of C2H2 zinc fingers with an acidic-rich region and a serine/threonine-rich sequence. These proteins bind specific DNA sequences, including the kappa-B motif (GGGACTTTCC), in the promoters and enhancer regions of several genes and viruses, including human immunodeficiency virus (HIV). ZAS genes span more than 150 kb and contain at least 10 exons, one of which is longer than 5.5 kb (Allen and Wu, 2004).[supplied by OMIM]