HKDC1

HKDC1
Identifiers
Aliases	HKDC1, hexokinase domain containing 1, RP92
External IDs	OMIM: 617221; MGI: 2384910; HomoloGene: 128937; GeneCards: HKDC1; OMA:HKDC1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	69,267,552 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	62,258,270 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; testicle; ; mucosa of ileum; ; mucosa of transverse colon; ; islet of Langerhans; ; gallbladder; ; body of pancreas; ; right uterine tube; ; human kidney;
	Top expressed in
	renal calyx; ; intestinal villus; ; epithelium of small intestine; ; jejunum; ; lateral recess; ; duodenum; ; ileum; ; yolk sac; ; lateral ventricle; ; choroid plexus of lateral ventricle;
	More reference expression data
	n/a
Gene ontology
Molecular function	kinase activity; transferase activity; nucleotide binding; fructokinase activity; mannokinase activity; glucokinase activity; hexokinase activity; ATP binding; phosphotransferase activity, alcohol group as acceptor; glucose binding;
Cellular component	cytosol; mitochondrion;
Biological process	cellular glucose homeostasis; hexose metabolic process; glycolytic process; carbohydrate phosphorylation; phosphorylation; glucose 6-phosphate metabolic process; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	80201
	216019
	ENSG00000156510
	ENSMUSG00000020080
	Q2TB90
	Q91W97
	NM_025130
	NM_145419
	NP_079406
	NP_663394
	Wikidata
View/Edit Human	View/Edit Mouse

Hexokinase domain containing 1 (HKDC1) is an enzyme which in humans is encoded by the HKDC1 gene on chromosome 10. It is a recently discovered hexokinase isoform that likely phosphorylates glucose in maternal metabolism during pregnancy.