HLTF

HLTF
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2MZN, 4HRE, 4HRH, 4S0N, 4XZF, 4XZG, 5BNH, 5K5F
Identifiers
Aliases	HLTF, HIP116, HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3, ZBU1, helicase-like transcription factor, helicase like transcription factor
External IDs	OMIM: 603257; MGI: 1196437; HomoloGene: 30136; GeneCards: HLTF; OMA:HLTF - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	149,086,554 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	20,172,654 bp
RNA expression pattern
	Top expressed in
	testicle; ; Pons; ; lateral nuclear group of thalamus; ; pars compacta; ; Epithelium of choroid plexus; ; pars reticulata; ; subthalamic nucleus; ; superior vestibular nucleus; ; external globus pallidus; ; cerebellar vermis;
	Top expressed in
	saccule; ; otic placode; ; otic vesicle; ; habenula; ; atrioventricular valve; ; transitional epithelium of urinary bladder; ; mesenteric lymph nodes; ; retinal pigment epithelium; ; blood; ; primitive streak;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; nucleotide binding; helicase activity; zinc ion binding; DNA-binding transcription activator activity, RNA polymerase II-specific; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; ATPase activity; protein binding; catalytic activity; nucleic acid binding; hydrolase activity; ATP binding; ubiquitin protein ligase binding; transferase activity; RNA binding; ubiquitin protein ligase activity;
Cellular component	cytoplasm; membrane; nucleolus; nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; metabolism; positive regulation of transcription by RNA polymerase II; protein ubiquitination; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	6596
	20585
	ENSG00000071794
	ENSMUSG00000002428
	Q14527
	Q6PCN7
	NM_003071; NM_139048; NM_001318934; NM_001318935
	NM_009210; NM_144959; NM_001355097
	NP_001305863; NP_001305864; NP_003062; NP_620636
	NP_033236; NP_001342026
	Wikidata
View/Edit Human	View/Edit Mouse

Helicase-like transcription factor is an enzyme that in humans is encoded by the HLTF gene.