HMGA1

HMGA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EZD, 2EZE, 2EZF, 2EZG
Identifiers
Aliases	HMGA1, HMG-R, HMGA1A, HMGIY, high mobility group AT-hook 1
External IDs	OMIM: 600701; MGI: 96160; HomoloGene: 128226; GeneCards: HMGA1; OMA:HMGA1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	34,246,231 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	27,782,648 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; embryo; ; mucosa of pharynx; ; ganglionic eminence; ; skin of abdomen; ; thymus; ; mucosa of transverse colon; ; skin of leg; ; nipple; ; appendix;
	Top expressed in
	epiblast; ; tail of embryo; ; yolk sac; ; genital tubercle; ; embryo; ; embryo; ; secondary oocyte; ; zygote; ; lip; ; ventricular zone;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	retinoid X receptor binding; retinoic acid receptor binding; enzyme binding; peroxisome proliferator activated receptor binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; nuclear receptor coactivator activity; protein binding; chromatin binding; DNA-binding transcription factor activity; 5'-deoxyribose-5-phosphate lyase activity; transcription factor binding; DNA-(apurinic or apyrimidinic site) endonuclease activity; cis-regulatory region sequence-specific DNA binding; minor groove of adenine-thymine-rich DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription coactivator activity; structural constituent of chromatin;
Cellular component	nucleus; nucleoplasm; cytosol; senescence-associated heterochromatin focus; chromosome; focal adhesion; transcription regulator complex; chromatin; RNA polymerase II transcription regulator complex;
Biological process	negative regulation of cell population proliferation; oncogene-induced cell senescence; establishment of integrated proviral latency; nucleosome disassembly; regulation of transcription, DNA-templated; positive regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; positive regulation of cellular senescence; negative regulation of transcription, DNA-templated; response to virus; DNA unwinding involved in DNA replication; transcription, DNA-templated; transcription by RNA polymerase II; nuclear transport; viral process; base-excision repair; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	3159
	15361
	ENSG00000137309
	ENSMUSG00000046711
	P17096
	P17095
NM_002131; NM_145899; NM_145901; NM_145902; NM_145903;
	NM_145904; NM_145905; NM_001319077; NM_001319078; NM_001319079; NM_001319080; NM_001319081; NM_001319082
NM_001025427; NM_001039356; NM_001166535; NM_001166536; NM_001166537;
	NM_001166539; NM_001166540; NM_001166541; NM_001166542; NM_001166543; NM_001166544; NM_001166545; NM_001166546; NM_016660
NP_001306006; NP_001306007; NP_001306008; NP_001306009; NP_001306010;
	NP_001306011; NP_002122; NP_665906; NP_665908; NP_665909; NP_665910; NP_665912
NP_001159948; NP_001159949; NP_001020598; NP_001034445; NP_001160007;
	NP_001160008; NP_001160009; NP_001160011; NP_001160012; NP_001160013; NP_001160014; NP_001160015; NP_001160016; NP_001160017; NP_001160018; NP_057869
	Wikidata
View/Edit Human	View/Edit Mouse

High-mobility group protein HMG-I/HMG-Y is a protein that in humans is encoded by the HMGA1 gene.