HNRNPAB

HNRNPAB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3S7R
Identifiers
Aliases	HNRNPAB, ABBP1, HNRPAB, heterogeneous nuclear ribonucleoprotein A/B
External IDs	OMIM: 602688; MGI: 1330294; HomoloGene: 74950; GeneCards: HNRNPAB; OMA:HNRNPAB - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	178,211,163 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	51,497,674 bp
RNA expression pattern
	Top expressed in
	mucosa of sigmoid colon; ; embryo; ; ganglionic eminence; ; human penis; ; mucosa of ileum; ; ventricular zone; ; mucosa of transverse colon; ; rectum; ; vulva; ; skin of thigh;
	Top expressed in
	primitive streak; ; abdominal wall; ; medial ganglionic eminence; ; condyle; ; hair follicle; ; vas deferens; ; endothelial cell of lymphatic vessel; ; Rostral migratory stream; ; renal corpuscle; ; Gonadal ridge;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; nucleic acid binding; sequence-specific DNA binding; protein binding; mRNA binding; RNA binding; sequence-specific double-stranded DNA binding;
Cellular component	cytoplasm; RNA polymerase II transcription regulator complex; nucleus; nucleoplasm; ribonucleoprotein complex;
Biological process	positive regulation of transcription, DNA-templated; epithelial to mesenchymal transition;
	Sources:Amigo / QuickGO
Orthologs
	3182
	15384
	ENSG00000197451
	ENSMUSG00000020358
	Q99729
	Q99020
	NM_031266; NM_004499
	NM_001048061; NM_010448
	NP_004490; NP_112556
	NP_001041526; NP_034578
	Wikidata
View/Edit Human	View/Edit Mouse

Heterogeneous nuclear ribonucleoprotein A/B, also known as HNRNPAB, is a protein which in humans is encoded by the HNRNPAB gene. Although this gene is named HNRNPAB in reference to its first cloning as an RNA binding protein with similarity to HNRNP A and HNRNP B, it is not a member of the HNRNP A/B subfamily of HNRNPs, but groups together closely with HNRNPD/AUF1 and HNRNPDL.