HNRNPC

HNRNPC
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1TXP, 1WF2, 2MXY, 2MZ1, 3LN4
Identifiers
Aliases	HNRNPC, C1, C2, HNRNP, HNRPC, SNRPC, heterogeneous nuclear ribonucleoprotein C (C1/C2), heterogeneous nuclear ribonucleoprotein C
External IDs	OMIM: 164020; MGI: 107795; HomoloGene: 74524; GeneCards: HNRNPC; OMA:HNRNPC - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	21,269,494 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	52,341,485 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; monocyte; ; left ovary; ; smooth muscle tissue; ; right uterine tube; ; epithelium of colon; ; right ovary; ; appendix;
	Top expressed in
	primitive streak; ; condyle; ; medial ganglionic eminence; ; fossa; ; abdominal wall; ; internal carotid artery; ; external carotid artery; ; renal corpuscle; ; endothelial cell of lymphatic vessel; ; migratory enteric neural crest cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; N6-methyladenosine-containing RNA binding; poly(U) RNA binding; mRNA 3'-UTR binding; protein binding; identical protein binding; nucleosomal DNA binding; nucleic acid binding; telomerase RNA binding; RNA binding;
Cellular component	cytosol; catalytic step 2 spliceosome; membrane; nucleoplasm; telomerase holoenzyme complex; extracellular exosome; spliceosomal complex; nucleus; actin cytoskeleton; extracellular region; protein-containing complex;
Biological process	negative regulation of telomere maintenance via telomerase; mRNA processing; osteoblast differentiation; 3'-UTR-mediated mRNA stabilization; mRNA splicing, via spliceosome; RNA splicing; RNA metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	3183
	15381
	ENSG00000092199
	ENSMUSG00000060373
	P07910
	Q9Z204
	NM_001077442; NM_001077443; NM_004500; NM_031314
NM_001170981; NM_001170982; NM_001170983; NM_001170984; NM_016884;
	NM_001360172; NM_001360173; NM_001360174; NM_001360175; NM_001360176; NM_001360177; NM_001360178; NM_001360179; NM_001360180; NM_001360181; NM_001360182; NM_001360183; NM_001360184
	NP_001070910; NP_001070911; NP_004491; NP_112604
NP_001164452; NP_001164453; NP_001164454; NP_001164455; NP_058580;
	NP_001347101; NP_001347102; NP_001347103; NP_001347104; NP_001347105; NP_001347106; NP_001347107; NP_001347108; NP_001347109; NP_001347110; NP_001347111; NP_001347112; NP_001347113
	Wikidata
View/Edit Human	View/Edit Mouse

Heterogeneous nuclear ribonucleoproteins C1/C2 is a protein that in humans is encoded by the HNRNPC gene.

It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART.