HOPX

HOPX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UHS, 2HI3
Identifiers
Aliases	HOPX, CAMEO, HOD, HOP, LAGY, NECC1, OB1, SMAP31, TOTO, HOP homeobox
External IDs	OMIM: 607275; MGI: 1916782; HomoloGene: 15859; GeneCards: HOPX; OMA:HOPX - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	56,681,899 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	77,262,968 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; corpus epididymis; ; skin of hip; ; mucosa of pharynx; ; human penis; ; oral cavity; ; skin of abdomen; ; vulva; ; right lung; ; upper lobe of left lung;
	Top expressed in
	right lung lobe; ; left lung; ; superior surface of tongue; ; right ventricle; ; cardiac muscle tissue of left ventricle; ; left lung lobe; ; gastrula; ; esophagus; ; interventricular septum; ; transitional epithelium of urinary bladder;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; nucleus;
Biological process	regulation of transcription by RNA polymerase II; negative regulation of cell differentiation; multicellular organism development; regulation of transcription, DNA-templated; transcription, DNA-templated; trophectodermal cell differentiation; chaperone-mediated protein complex assembly; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	84525
	74318
	ENSG00000171476
	ENSMUSG00000059325
	Q9BPY8
	Q8R1H0
	NM_001145459; NM_001145460; NM_032495; NM_139211; NM_139212
	NM_001159900; NM_001159901; NM_175606
	NP_001138931; NP_001138932; NP_115884; NP_631957; NP_631958
	NP_001153372; NP_001153373; NP_783199
	Wikidata
View/Edit Human	View/Edit Mouse

Homeodomain-only protein is a protein that in humans is encoded by the HOPX gene. It is an important regulator of cardiac development and a marker of hippocampal neural stem cells.