HOXB4

HOXB4
Identifiers
Aliases	HOXB4, HOX-2.6, HOX2, HOX2F, homeobox B4
External IDs	OMIM: 142965; MGI: 96185; HomoloGene: 32095; GeneCards: HOXB4; OMA:HOXB4 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	48,578,350 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	96,212,464 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; muscle layer of sigmoid colon; ; gastric mucosa; ; endometrium; ; Descending thoracic aorta; ; left uterine tube; ; human kidney; ; right lung; ; fundus; ; right adrenal gland;
	Top expressed in
	tail of embryo; ; thoracic vertebral column; ; migratory enteric neural crest cell; ; medullary collecting duct; ; ascending aorta; ; granulocyte; ; female urethra; ; inner root sheath; ; primitive streak; ; renal corpuscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific;
Cellular component	nucleus; centrosome;
Biological process	embryonic skeletal system morphogenesis; multicellular organism development; definitive hemopoiesis; somatic stem cell division; skeletal system morphogenesis; cell population proliferation; positive regulation of stem cell differentiation; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; spleen development; hematopoietic stem cell differentiation; morphogenesis of an epithelial sheet; transcription, DNA-templated; anterior/posterior pattern specification; positive regulation of transcription by RNA polymerase II; bone marrow development; hemopoiesis; skeletal system development;
	Sources:Amigo / QuickGO
Orthologs
	3214
	15412
	ENSG00000182742
	ENSMUSG00000038692
	P17483
	P10284
	NM_024015
	NM_010459
	NP_076920
	NP_034589
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-B4 is a protein that in humans is encoded by the HOXB4 gene.