HOXC6

HOXC6
Identifiers
Aliases	HOXC6, CP25, HHO.C8, HOX3, HOX3C, homeobox C6
External IDs	OMIM: 142972; MGI: 96197; HomoloGene: 19533; GeneCards: HOXC6; OMA:HOXC6 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	54,030,823 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,920,313 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; caput epididymis; ; germinal epithelium; ; nipple; ; saphenous vein; ; corpus epididymis; ; skin of hip; ; Skeletal muscle tissue of rectus abdominis; ; spinal ganglia; ; lactiferous duct;
	Top expressed in
	tail of embryo; ; thoracic vertebral column; ; efferent ductule; ; muscle of thigh; ; genital tubercle; ; female urethra; ; adrenal gland; ; male urethra; ; lumbar subsegment of spinal cord; ; yolk sac;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; transcription corepressor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;
Cellular component	nucleus; nucleoplasm; cytosol;
Biological process	regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription, DNA-templated; anterior/posterior pattern specification; embryonic skeletal system development; negative regulation of nucleic acid-templated transcription; multicellular organism development; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3223
	15425
	ENSG00000197757
	ENSMUSG00000001661
	P09630
	P10629
	NM_153693; NM_004503
	NM_010465
	NP_004494; NP_710160
	NP_034595
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. Hox-C6 expression is highest in the fallopian tube and ovary. HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.