Hippocalcin-like protein 1

HPCAL1
Identifiers
Aliases	HPCAL1, BDR1, HLP2, VILIP-3, hippocalcin like 1
External IDs	OMIM: 600207; MGI: 1855689; HomoloGene: 37586; GeneCards: HPCAL1; OMA:HPCAL1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	10,427,617 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	17,791,933 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; paraflocculus of cerebellum; ; right hemisphere of cerebellum; ; frontal pole; ; Brodmann area 10; ; lateral nuclear group of thalamus; ; cingulate gyrus; ; anterior cingulate cortex; ; right frontal lobe; ; right lung;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; entorhinal cortex; ; anterior amygdaloid area; ; dorsomedial hypothalamic nucleus; ; perirhinal cortex; ; paraventricular nucleus of hypothalamus; ; ventral tegmental area; ; granulocyte; ; habenula;
	More reference expression data
	; ;
	More reference expression data
Orthologs
	3241
	53602
	ENSG00000115756
	ENSMUSG00000071379
	P37235
	P62748
	NM_001258357; NM_001258358; NM_001258359; NM_002149; NM_134421
	NM_016677; NM_001361645
	NP_001245286; NP_001245287; NP_001245288; NP_002140; NP_602293
	NP_057886; NP_001348574
	Wikidata
View/Edit Human	View/Edit Mouse

Hippocalcin-like protein 1 is a protein that in humans is encoded by the HPCAL1 gene.

The protein encoded by this gene is a member of the neuron-specific calcium-binding proteins family found in the retina and brain. It is highly similar to human hippocalcin protein, and nearly identical to rat and mouse hippocalcin like-1 proteins. It may be involved in the calcium-dependent regulation of rhodopsin phosphorylation, and may be of relevance to neuronal signaling in the central nervous system. There are two alternatively spliced transcript variants of this gene, with multiple polyadenylation sites.