HPS6

HPS6
Identifiers
Aliases	HPS6, BLOC2S3, biogenesis of lysosomal organelles complex 2 subunit 3, HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
External IDs	OMIM: 607522; MGI: 2181763; HomoloGene: 11691; GeneCards: HPS6; OMA:HPS6 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	102,068,036 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	45,994,612 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; gingival epithelium; ; stromal cell of endometrium; ; mucosa of transverse colon; ; monocyte; ; apex of heart; ; gonad; ; testicle; ; pancreatic ductal cell; ; mucosa of ileum;
	Top expressed in
	primary oocyte; ; granulocyte; ; secondary oocyte; ; right kidney; ; proximal tubule; ; morula; ; muscle of thigh; ; mesenteric lymph nodes; ; embryo; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTP-dependent protein binding; protein binding;
Cellular component	cytoplasm; organelle membrane; BLOC-2 complex; endosome; cytosol; early endosome membrane; endoplasmic reticulum; membrane; intracellular membrane-bounded organelle; lysosome; lysosomal membrane;
Biological process	protein localization to membrane; pigmentation; blood coagulation; lysosome localization; organelle organization; melanocyte differentiation;
	Sources:Amigo / QuickGO
Orthologs
	79803
	20170
	ENSG00000166189
	ENSMUSG00000074811
	Q86YV9
	Q8BLY7
	NM_024747
	NM_176785
	NP_079023
	NP_789742
	Wikidata
View/Edit Human	View/Edit Mouse

Hermansky–Pudlak syndrome 6 (HPS6), also known as ruby-eye protein homolog (Ru), is a protein that in humans is encoded by the HPS6 gene.