HPSE2

HPSE2
Identifiers
Aliases	HPSE2, HPA2, HPR2, UFS, UFS1, heparanase 2 (inactive)
External IDs	OMIM: 613469; MGI: 2685814; HomoloGene: 19680; GeneCards: HPSE2; OMA:HPSE2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	99,235,862 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	43,376,794 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; canal of the cervix; ; gastric mucosa; ; ectocervix; ; popliteal artery; ; tibial arteries; ; Hypothalamus; ; caudate nucleus; ; putamen; ; C1 segment;
	Top expressed in
	genital tubercle; ; pineal gland; ; spermatid; ; zygote; ; migratory enteric neural crest cell; ; hand; ; urinary bladder; ; lobe of prostate; ; lip; ; Gonadal ridge;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	heparan sulfate proteoglycan binding; heparanase activity; hydrolase activity, acting on glycosyl bonds;
Cellular component	extracellular region; plasma membrane; intracellular anatomical structure; membrane; extracellular matrix;
Biological process	glycosaminoglycan catabolic process; positive regulation of cell population proliferation; extracellular matrix organization; biological process;
	Sources:Amigo / QuickGO
Orthologs
	60495
	545291
	ENSG00000172987
	ENSMUSG00000074852
	Q8WWQ2
	B2RY83
	NM_001166244; NM_001166245; NM_001166246; NM_021828
	NM_001081257
	NP_001159716; NP_001159717; NP_001159718; NP_068600
	NP_001074726
	Wikidata
View/Edit Human	View/Edit Mouse

Heparanase-2 is an enzyme that in humans is encoded by the HPSE2 gene.

It may be associated with urofacial syndrome.