HSD17B11

HSD17B11
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1YB1
Identifiers
Aliases	HSD17B11, 17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2, hydroxysteroid (17-beta) dehydrogenase 11, hydroxysteroid 17-beta dehydrogenase 11
External IDs	OMIM: 612831; MGI: 2149821; HomoloGene: 69209; GeneCards: HSD17B11; OMA:HSD17B11 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	87,391,188 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	104,169,785 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; mucosa of colon; ; duodenum; ; mucosa of sigmoid colon; ; rectum; ; mucosa of ileum; ; monocyte; ; gallbladder; ; mucosa of transverse colon; ; blood;
	Top expressed in
	vestibular membrane of cochlear duct; ; pyloric antrum; ; epithelium of stomach; ; mucous cell of stomach; ; iris; ; intestinal villus; ; stria vascularis; ; Ileal epithelium; ; left lobe of liver; ; duodenum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; steroid dehydrogenase activity; estradiol 17-beta-dehydrogenase activity;
Cellular component	cytoplasm; extracellular region; cytosol; lipid droplet;
Biological process	estrogen biosynthetic process; androgen catabolic process; lipid metabolism; steroid biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	51170
	114664
	ENSG00000198189
	ENSMUSG00000029311
	Q8NBQ5
	Q9EQ06
	NM_016245
	NM_053262
	NP_057329
	NP_444492
	Wikidata
View/Edit Human	View/Edit Mouse

Estradiol 17-beta-dehydrogenase 11 is an enzyme that in humans is encoded by the HSD17B11 gene.

HSD17B11 expression has been linked to higher survival rates for lung cancer patients.