HSD17B3

HSD17B3
Identifiers
Aliases	HSD17B3, EDH17B3, SDR12C2, hydroxysteroid (17-beta) dehydrogenase 3, hydroxysteroid 17-beta dehydrogenase 3
External IDs	OMIM: 605573; MGI: 107177; HomoloGene: 20089; GeneCards: HSD17B3; OMA:HSD17B3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	96,302,176 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	64,237,044 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; testicle; ; right lobe of liver; ; C1 segment; ; tibial nerve; ; substantia nigra; ; gastric mucosa; ; left lobe of thyroid gland; ; olfactory zone of nasal mucosa;
	Top expressed in
	Gonadal ridge; ; testicle; ; embryo; ; spermatocyte; ; seminiferous tubule; ; embryo; ; right ventricle; ; gastrula; ; blastocyst; ; adrenal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	testosterone 17-beta-dehydrogenase (NADP+) activity; oxidoreductase activity; testosterone dehydrogenase (NAD+) activity; testosterone dehydrogenase [NAD(P) activity];
Cellular component	endoplasmic reticulum membrane; intracellular membrane-bounded organelle; endoplasmic reticulum;
Biological process	testosterone biosynthetic process; steroid biosynthetic process; lipid metabolism; androgen biosynthetic process; male genitalia development;
	Sources:Amigo / QuickGO
Orthologs
	3293
	15487
	ENSG00000130948
	ENSMUSG00000033122
	P37058; Q6FH62
	P70385
	NM_000197
	NM_008291
	NP_000188; NP_000188.1
	NP_032317
	Wikidata
View/Edit Human	View/Edit Mouse

17β-Hydroxysteroid dehydrogenase 3 (17β-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis.