HSPH1

HSPH1
Identifiers
Aliases	HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25, heat shock protein family H (Hsp110) member 1
External IDs	OMIM: 610703; MGI: 105053; HomoloGene: 21322; GeneCards: HSPH1; OMA:HSPH1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	31,162,388 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	149,559,841 bp
RNA expression pattern
	Top expressed in
	gonad; ; bronchial epithelial cell; ; nucleus accumbens; ; postcentral gyrus; ; caudate nucleus; ; Brodmann area 23; ; putamen; ; Region I of hippocampus proper; ; Brodmann area 9; ; superior frontal gyrus;
	Top expressed in
	tail of embryo; ; genital tubercle; ; primitive streak; ; barrel cortex; ; Paneth cell; ; ventromedial nucleus; ; facial motor nucleus; ; arcuate nucleus; ; utricle; ; cingulate gyrus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; alpha-tubulin binding; protein binding; ATP binding; adenyl-nucleotide exchange factor activity;
Cellular component	cytoplasm; cytosol; endocytic vesicle lumen; nucleoplasm; extracellular region; microtubule; extracellular exosome; nucleus; protein-containing complex;
Biological process	negative regulation of establishment of protein localization to mitochondrion; positive regulation of protein tyrosine kinase activity; negative regulation of p38MAPK cascade; negative regulation of apoptotic signaling pathway; receptor-mediated endocytosis; chaperone cofactor-dependent protein refolding; positive regulation of NK T cell activation; response to unfolded protein; regulation of cellular response to heat; negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide; positive regulation of MHC class I biosynthetic process; positive regulation of transcription by RNA polymerase II; regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	10808
	15505
	ENSG00000120694
	ENSMUSG00000029657
	Q92598
	Q61699
	NM_001286503; NM_001286504; NM_001286505; NM_006644; NM_001349704
	NM_013559; NM_001347534
	NP_001273432; NP_001273433; NP_001273434; NP_006635; NP_001336633
	NP_001334463; NP_038587
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene.