HUS1

HUS1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3A1J, 3G65, 3GGR
Identifiers
Aliases	HUS1, hHUS1 checkpoint clamp component
External IDs	OMIM: 603760; MGI: 1277962; HomoloGene: 37932; GeneCards: HUS1; OMA:HUS1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	47,979,615 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	8,961,191 bp
RNA expression pattern
	Top expressed in
	gonad; ; monocyte; ; sural nerve; ; Achilles tendon; ; islet of Langerhans; ; rectum; ; epithelium of colon; ; muscle of thigh; ; gastrocnemius muscle; ; stromal cell of endometrium;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; tail of embryo; ; genital tubercle; ; primitive streak; ; substantia nigra; ; proximal tubule; ; ureter; ; abdominal wall;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	site of double-strand break; cytoplasm; cytosol; nucleoplasm; checkpoint clamp complex; nucleolus; nucleus;
Biological process	regulation of protein phosphorylation; nucleotide-excision repair; meiotic DNA integrity checkpoint signaling; embryo development; mitotic cell cycle checkpoint signaling; mitotic intra-S DNA damage checkpoint signaling; negative regulation of DNA replication; cellular response to DNA damage stimulus; protein phosphorylation; mitotic DNA replication checkpoint signaling; cellular response to ionizing radiation; response to UV; double-strand break repair via homologous recombination; DNA damage checkpoint signaling; DNA repair; embryo development ending in birth or egg hatching; telomere maintenance; DNA replication; regulation of signal transduction by p53 class mediator;
	Sources:Amigo / QuickGO
Orthologs
	3364
	15574
	ENSG00000136273
	ENSMUSG00000020413
	O60921
	Q8BQY8
	NM_004507; NM_001363683
	NM_008316; NM_001303532; NM_001303610
	NP_004498; NP_001350612
	NP_001290461; NP_001290539; NP_032342
	Wikidata
View/Edit Human	View/Edit Mouse

Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.