Half and half nail

Half and half nails
Other namesLindsay's nails
Half and half nails
SpecialtyInternal medicine, Dermatology
Causesincreased β-MSH
Risk factorshemodialysis, renal transplant
Diagnostic methodPhysical examination
Differential diagnosisTerry's nails

Half and half nails (also known as "Lindsay's nails") show the proximal portion of the nail white and the distal half red, pink, or brown, with a sharp line of demarcation between the two halves.:785 The darker distal discoloration does not fade on pressure, which differentiates Lindsay's nails from Terry's nails. The discoloration is thought to be due to β-melanocyte–stimulating hormone. Seventy percent of hemodialysis patients and 56% of renal transplant patients have at least one type of nail abnormality. Absence of lunula, splinter hemorrhage, and half and half nails were significantly more common in hemodialysis patients, while leukonychia was significantly more common in transplant patients.:785:659