Haloxazolam

Haloxazolam
Clinical data
Trade names	Somelin (JP)
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	BR: Class B1 (Psychoactive drugs); CA: Schedule IV; DE: Anlage III (Special prescription form required); US: Schedule IV;
Pharmacokinetic data
Metabolism	Hepatic
Excretion	Renal
Identifiers
	IUPAC name 10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one;
CAS Number	59128-97-1 ;
PubChem CID	3563;
DrugBank	DB01476 ;
ChemSpider	3442 ;
UNII	M448L2V8XP;
KEGG	D01758 ;
ChEMBL	ChEMBL2104461 ;
CompTox Dashboard (EPA)	DTXSID60866740 ;
Chemical and physical data
Formula	C17H14BrFN2O2
Molar mass	377.213 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Fc1ccccc1C42OCCN2CC(=O)Nc3c4cc(Br)cc3;
	InChI InChI=1S/C17H14BrFN2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22) ; Key:XDKCGKQHVBOOHC-UHFFFAOYSA-N ;
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Haloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative. It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment of insomnia. A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.