Herpes simplex virus protein vmw65

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	16vp

Alpha trans-inducing protein (Alpha-TIF)
Alpha trans-inducing protein (Alpha-TIF)
	Structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16.
Identifiers
Symbol	Alpha_TIF
Pfam	PF02232
InterPro	IPR003174
SMART	SM00814
SCOP2	16vp / SCOPe / SUPFAM
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	16vp

Vmw65, also known as VP16 or α-TIF (Trans Inducing Factor) is a trans-acting protein that forms a complex with the host transcription factors Oct-1 and HCF to induce immediate early gene transcription in the herpes simplex viruses.

VP16 is a strong transactivator and is often used in Y2H systems as the activation domain of the system.