Circuito Sur de Oriente

6–20 (Carretera Granma)
6–4 (Carretera a Manzanillo)
Circuito Sur de Oriente (CSO)
; 6–20 (Carretera Granma); 6–4 (Carretera a Manzanillo) Circuito Sur de Oriente (CSO)
Southern Circuit of the Orient
	The CSO across the municipality of Guamá; with the Sierra Maestra in background
Route information
Length	347 km (216 mi)
6–4
East end	Bayamo Beltway
Major intersections	Bayamo–Montero Road; 6–122; 6–76; Bayamo–Montero Road (under construction); 6–20
West end	Cabo Cruz
6–20
West end	6–4
East end	CC
Location
Country	Cuba
Major cities	Bayamo, Manzanillo, Campechuela, Niquero, Pilón, Chivirico, Santiago de Cuba
Highway system
	Roads in Cuba;

The Circuito Sur de Oriente (CSO), meaning "Southern Circuit of the Orient", is a west-east highway connecting Bayamo to Santiago de Cuba, through Manzanillo, Niquero and the southern coastal side of eastern Cuba, below the Sierra Maestra mountain range. Also known as Circuito Guacanayabo-Sur de Oriente, because it crosses the Gulf of Guacanayabo, the name Oriente (meaning "Orient"), refers to the ancient and former Oriente Province. With a length of 347 km, it is the fourth-longest Cuban highway after the "Carretera Central", the "Circuito Norte" and the "Circuito Sur".