Human coronavirus HKU1
| Human coronavirus HKU1 | |
|---|---|
| Formation of HcoV-HKU1 | |
| Virus classification | |
| (unranked): | Virus | 
| Realm: | Riboviria | 
| Kingdom: | Orthornavirae | 
| Phylum: | Pisuviricota | 
| Class: | Pisoniviricetes | 
| Order: | Nidovirales | 
| Family: | Coronaviridae | 
| Genus: | Betacoronavirus | 
| Subgenus: | Embecovirus | 
| Species: | Betacoronavirus hongkonense  | 
| Synonyms | |
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Human coronavirus HKU1 (HCoV-HKU1, Betacoronavirus hongkonense) is a species of coronavirus in humans and animals. It causes an upper respiratory disease with symptoms of the common cold, but can advance to pneumonia and bronchiolitis. It was first discovered in January 2004 from one man in Hong Kong. Subsequent research revealed it has global distribution and earlier genesis.
The virus is an enveloped, positive-sense, single-stranded RNA virus which enters its host cell by binding to the N-acetyl-9-O-acetylneuraminic acid receptor. It has the Hemagglutinin esterase (HE) gene, which distinguishes it as a member of the genus Betacoronavirus and subgenus Embecovirus.