Hyperimmunoglobulin E syndrome

Hyper-IgE syndrome
Other namesHIES
The structure of the Immunoglobulin E (IgE) antibody.
SpecialtyImmunology 

Hyperimmunoglobulinemia E syndrome (HIES), of which the autosomal dominant form is called Job's syndrome or Buckley syndrome, is a heterogeneous group of immune disorders. Job's is also very rare at about 300 cases currently in the literature.