IFIT1

IFIT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4HOU
Identifiers
Aliases	IFIT1, C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561, interferon induced protein with tetratricopeptide repeats 1
External IDs	OMIM: 147690; MGI: 2148249; HomoloGene: 78213; GeneCards: IFIT1; OMA:IFIT1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	34,618,143 bp
RNA expression pattern
	Top expressed in
	Pons; ; trigeminal ganglion; ; biceps brachii; ; glomerulus; ; metanephric glomerulus; ; palpebral conjunctiva; ; subthalamic nucleus; ; germinal epithelium; ; amniotic fluid; ; parietal pleura;
	Top expressed in
	epithelium of small intestine; ; zygote; ; jejunum; ; secondary oocyte; ; ileum; ; interventricular septum; ; granulocyte; ; primary oocyte; ; duodenum; ; migratory enteric neural crest cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	cytoplasm; host cell; cytosol;
Biological process	negative regulation of helicase activity; response to virus; positive regulation of viral genome replication; negative regulation of viral genome replication; negative regulation of defense response to virus by host; cellular response to type I interferon; viral process; intracellular transport of viral protein in host cell; negative regulation of protein binding; type I interferon signaling pathway; innate immune response; regulation of defense response to virus; cellular response to exogenous dsRNA; immune system process; defense response to virus; response to bacterium; cellular response to interferon-beta;
	Sources:Amigo / QuickGO
Orthologs
	3434
	112419
	n/a
	ENSMUSG00000067297
	P09914
	Q3U687
	NM_001548; NM_001270927; NM_001270928; NM_001270929; NM_001270930
	NM_053217; NM_001362130
	NP_001257856; NP_001257857; NP_001257858; NP_001257859; NP_001539
	NP_444447; NP_001349059
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-induced protein with tetratricopeptide repeats 1 is a protein that in humans is encoded by the IFIT1 gene.