Interferon-induced transmembrane protein 2

IFITM2
Identifiers
Aliases	IFITM2, 1-8D, DSPA2c, interferon induced transmembrane protein 2
External IDs	OMIM: 605578; MGI: 1933382; HomoloGene: 74574; GeneCards: IFITM2; OMA:IFITM2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	309,397 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	140,535,900 bp
RNA expression pattern
	Top expressed in
	blood; ; right lung; ; pericardium; ; periodontal fiber; ; spleen; ; upper lobe of left lung; ; left uterine tube; ; Descending thoracic aorta; ; olfactory bulb; ; granulocyte;
	Top expressed in
	adrenal gland; ; granulocyte; ; uterus; ; lung; ; urinary bladder; ; lip; ; white adipose tissue; ; zone of skin; ; heart; ; epiblast;
	More reference expression data
	n/a
Orthologs
	10581
	80876
	ENSG00000185201
	ENSMUSG00000060591
	Q01629
	Q99J93
	NM_006435
	NM_030694
	NP_006426
	NP_109619
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-induced transmembrane protein 2 is a protein that in humans is encoded by the IFITM2 gene. IFITM1 is a member of the IFITM family (Interferon-induced transmembrane protein) which is encoded by IFITM genes.

As the name implies, these genes are induced by interferon and form part of its signaling pathway. In the absence of interferon stimulation, IFITM proteins can express broadly in tissues and cell lines. In humans, IFITM1, IFITM2 and IFITM3 are able to express in different tissues and cells while the expression of IFITM5 is limited to osteoblasts.