IFT74

IFT74
Identifiers
Aliases	IFT74, CCDC2, CMG-1, CMG1, intraflagellar transport 74, BBS20, BBS22, SPGF58, JBTS40
External IDs	OMIM: 608040; MGI: 1914944; HomoloGene: 11831; GeneCards: IFT74; OMA:IFT74 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	27,066,134 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	94,693,229 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; caput epididymis; ; right uterine tube; ; Achilles tendon; ; corpus epididymis; ; left testis; ; right testis; ; testicle; ; gonad; ; mucosa of paranasal sinus;
	Top expressed in
	seminiferous tubule; ; olfactory epithelium; ; spermatid; ; spermatocyte; ; maxillary prominence; ; mandibular prominence; ; saccule; ; Gonadal ridge; ; otic vesicle; ; Epithelium of choroid plexus;
	More reference expression data
	n/a
Gene ontology
Molecular function	chromatin binding; beta-tubulin binding; protein binding;
Cellular component	intraciliary transport particle B; centrosome; cell projection; ciliary tip; motile cilium; cytoplasmic vesicle; nucleus; cilium;
Biological process	Notch signaling pathway; intraciliary transport; heart development; keratinocyte development; determination of left/right symmetry; cell projection organization; epidermis development; negative regulation of epithelial cell proliferation; positive regulation of cell adhesion mediated by integrin; positive regulation of transcription by RNA polymerase II; intraciliary transport involved in cilium assembly; cilium assembly; non-motile cilium assembly;
	Sources:Amigo / QuickGO
Orthologs
	80173
	67694
	ENSG00000096872
	ENSMUSG00000028576
	Q96LB3
	Q8BKE9
	NM_001099222; NM_001099223; NM_001099224; NM_025103; NM_001349928
	NM_001290568; NM_026319
	NP_001092692; NP_001092693; NP_001092694; NP_079379; NP_001336857
	NP_001277497; NP_080595
	Wikidata
View/Edit Human	View/Edit Mouse

Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene.

BCMG1 is upregulated by umbilical vein endothelial cells during capillary morphogenesis.