IGFBP2

IGFBP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2H7T
Identifiers
Aliases	IGFBP2, IBP2, IGF-BP53, insulin like growth factor binding protein 2
External IDs	OMIM: 146731; MGI: 96437; HomoloGene: 499; GeneCards: IGFBP2; OMA:IGFBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	216,664,436 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	72,891,633 bp
RNA expression pattern
	Top expressed in
	Descending thoracic aorta; ; ascending aorta; ; decidua; ; right coronary artery; ; body of stomach; ; ventricular zone; ; ganglionic eminence; ; olfactory zone of nasal mucosa; ; epithelium of bronchus; ; bronchial epithelial cell;
	Top expressed in
	choroid plexus of fourth ventricle; ; calvaria; ; vestibular sensory epithelium; ; Epithelium of choroid plexus; ; corneal stroma; ; efferent ductule; ; optic nerve; ; transitional epithelium of urinary bladder; ; left lobe of liver; ; molar;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	insulin-like growth factor binding; growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding; protein binding; signaling receptor binding;
Cellular component	extracellular region; apical plasma membrane; extracellular exosome; cytoplasmic vesicle; extracellular space;
Biological process	response to estradiol; response to retinoic acid; response to nutrient; female pregnancy; response to steroid hormone; response to mechanical stimulus; ageing; response to glucocorticoid; response to lithium ion; response to estrogen; regulation of insulin-like growth factor receptor signaling pathway; cellular response to hormone stimulus; regulation of cell growth; regulation of growth; negative regulation of canonical Wnt signaling pathway; signal transduction; positive regulation of activated T cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	3485
	16008
	ENSG00000115457
	ENSMUSG00000039323
	P18065
	P47877
	NM_001313990; NM_001313992; NM_001313993; NM_000597
	NM_008342; NM_001310659
	NP_000588; NP_001300919; NP_001300921; NP_001300922
	NP_001297588; NP_032368
	Wikidata
View/Edit Human	View/Edit Mouse

Insulin-like growth factor-binding protein 2 is a protein that in humans is encoded by the IGFBP2 gene.