IGFBP4

IGFBP4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WQJ, 2DSP, 2DSQ, 2DSR
Identifiers
Aliases	IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4, insulin like growth factor binding protein 4
External IDs	OMIM: 146733; MGI: 96439; HomoloGene: 1192; GeneCards: IGFBP4; OMA:IGFBP4 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	40,457,725 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	98,945,218 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; decidua; ; right ovary; ; left ovary; ; left uterine tube; ; right lobe of liver; ; right lobe of thyroid gland; ; canal of the cervix; ; body of uterus; ; smooth muscle tissue;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; Gonadal ridge; ; calvaria; ; aortic valve; ; ascending aorta; ; vestibular sensory epithelium; ; molar; ; atrium; ; tunica adventitia of aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	insulin-like growth factor I binding; insulin-like growth factor II binding; signaling receptor binding; insulin-like growth factor binding; growth factor binding; protein binding;
Cellular component	extracellular region; extracellular space; endoplasmic reticulum lumen;
Biological process	skeletal system development; regulation of growth; DNA metabolic process; regulation of insulin-like growth factor receptor signaling pathway; regulation of glucose metabolic process; cell population proliferation; inflammatory response; positive regulation of insulin-like growth factor receptor signaling pathway; type B pancreatic cell proliferation; negative regulation of canonical Wnt signaling pathway; regulation of cell growth; signal transduction; positive regulation of MAPK cascade; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	3487
	16010
	ENSG00000141753
	ENSMUSG00000017493
	P22692
	P47879
	NM_001552
	NM_010517
	NP_001543
	NP_034647
	Wikidata
View/Edit Human	View/Edit Mouse

Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4 gene.