IL1RAPL2

IL1RAPL2
Identifiers
Aliases	IL1RAPL2, IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1, interleukin 1 receptor accessory protein like 2
External IDs	OMIM: 300277; MGI: 1913106; HomoloGene: 9681; GeneCards: IL1RAPL2; OMA:IL1RAPL2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	105,767,829 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	137,747,695 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; prefrontal cortex; ; right lobe of liver; ; skin of hip; ; Brodmann area 9; ; placenta; ; urinary bladder; ; gallbladder; ; primary visual cortex;
	Top expressed in
	multiform layer of neocortex; ; internal granular layer; ; Purkinje cell; ; external pyramidal layer of neocortex; ; embryo; ; internal pyramidal layer of neocortex; ; barrel cortex; ; primary visual cortex; ; median eminence; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	interleukin-1, type II, blocking receptor activity; interleukin-1 receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; glutamatergic synapse;
Biological process	central nervous system development; signal transduction; cytokine-mediated signaling pathway; regulation of presynapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	26280
	60367
	ENSG00000189108
	ENSMUSG00000059203
	Q9NP60
	Q9ERS6
	NM_017416
	NM_030688
	NP_059112
	NP_109613
	Wikidata
View/Edit Human	View/Edit Mouse

X-linked interleukin-1 receptor accessory protein-like 2 is a protein that in humans is encoded by the IL1RAPL2 gene.

The protein encoded by this gene is a member of the interleukin 1 receptor family. This protein is similar to the interleukin 1 accessory proteins, and is most closely related to interleukin 1 receptor accessory protein-like 1 (IL1RAPL1). This gene and IL1RAPL1 are located at a region on chromosome X that is associated with X-linked non-syndromic mental retardation.