IL1RL1

IL1RL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4KC3
Identifiers
Aliases	IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1, interleukin 1 receptor like 1
External IDs	OMIM: 601203; MGI: 98427; HomoloGene: 2862; GeneCards: IL1RL1; OMA:IL1RL1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	102,352,037 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	40,504,575 bp
RNA expression pattern
	Top expressed in
	upper lobe of left lung; ; decidua; ; right lung; ; cartilage tissue; ; lower lobe of lung; ; left adrenal gland; ; left adrenal cortex; ; right adrenal gland; ; human kidney; ; body of stomach;
	Top expressed in
	endothelial cell of lymphatic vessel; ; granulocyte; ; embryo; ; duodenum; ; lip; ; ileum; ; jejunum; ; muscle of thigh; ; esophagus; ; lactiferous gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interleukin-33 receptor activity; interleukin-1 receptor activity; cytokine receptor activity; protein binding; interleukin-33 binding;
Cellular component	integral component of membrane; external side of plasma membrane; membrane; extracellular region; plasma membrane; extracellular matrix;
Biological process	negative regulation of T-helper 1 type immune response; positive regulation of inflammatory response; negative regulation of interferon-gamma production; positive regulation of macrophage activation; negative regulation of I-kappaB kinase/NF-kappaB signaling; signal transduction; immune response; positive regulation of interleukin-5 production; interleukin-33-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9173
	17082
	ENSG00000115602
	ENSMUSG00000026069
	Q01638
	P14719
	NM_001282408; NM_003856; NM_016232; NM_173459
	NM_001025602; NM_001294171; NM_010743
	NP_001269337; NP_003847; NP_057316
	NP_001020773; NP_001281100; NP_034873
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a protein that in humans is encoded by the IL1RL1 gene.