Interleukin 37

IL37
Identifiers
Aliases	IL37, FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1, interleukin 37, IL-23
External IDs	OMIM: 605510; HomoloGene: 105713; GeneCards: IL37; OMA:IL37 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	112,918,882 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; skin of leg; ; skin of thigh; ; nipple; ; skin of abdomen; ; vena cava; ; skin of hip; ; subthalamic nucleus; ; body of tongue; ; ventral tegmental area;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; interleukin-1 receptor binding;
Cellular component	extracellular region; extracellular space; nucleus; cytoplasm; intracellular membrane-bounded organelle; nucleoplasm; cytosol;
Biological process	inflammatory response; immune response; cytokine-mediated signaling pathway; regulation of signaling receptor activity; cellular response to cytokine stimulus; neutrophil chemotaxis; positive regulation of interleukin-6 production; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of JNK cascade; cellular response to lipopolysaccharide;
	Sources:Amigo / QuickGO
Orthologs
	27178
	n/a
	ENSG00000125571
	n/a
	Q9NZH6
	n/a
	NM_014439; NM_173202; NM_173203; NM_173204; NM_173205
	n/a
	NP_055254; NP_775294; NP_775295; NP_775296; NP_775297
	n/a
	Wikidata
View/Edit Human

Interleukin 37 (IL-37), also known as Interleukin-1 family member 7 (IL-1F7), is an anti-inflammatory cytokine important for the downregulation of pro-inflammatory cytokine production as well as the suppression of tumor cell growth.