IMMP2L

IMMP2L
Identifiers
Aliases	IMMP2L, IMMP2L-IT1, IMP2, IMP2-LIKE, inner mitochondrial membrane peptidase subunit 2
External IDs	OMIM: 605977; MGI: 2135611; HomoloGene: 6607; GeneCards: IMMP2L; OMA:IMMP2L - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	111,562,517 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	42,002,371 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; deltoid muscle; ; Achilles tendon; ; quadriceps femoris muscle; ; testicle; ; vastus lateralis muscle; ; gonad; ; Skeletal muscle tissue of biceps brachii; ; human kidney; ; tibial arteries;
	Top expressed in
	spermatid; ; brown adipose tissue; ; intercostal muscle; ; seminiferous tubule; ; spermatocyte; ; left lobe of liver; ; interventricular septum; ; myocardium of ventricle; ; right ventricle; ; tunica adventitia of aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity; serine-type peptidase activity; hydrolase activity;
Cellular component	integral component of membrane; membrane; mitochondrion; mitochondrial inner membrane; mitochondrial inner membrane peptidase complex;
Biological process	blood circulation; protein processing involved in protein targeting to mitochondrion; proteolysis; cellular response to DNA damage stimulus; brain development; mitochondrial respiratory chain complex assembly; spermatogenesis; ovarian follicle development; respiratory electron transport chain; cerebellum vasculature development; ovulation; superoxide metabolic process; signal peptide processing;
	Sources:Amigo / QuickGO
Orthologs
	83943
	93757
	ENSG00000184903
	ENSMUSG00000056899
	Q96T52
	Q8BPT6
NM_001244606; NM_032549; NM_001350959; NM_001350960; NM_001350961;
	NM_001350962; NM_001350963; NM_001350964
	NM_053122
NP_001231535; NP_115938; NP_001337888; NP_001337889; NP_001337890;
	NP_001337891; NP_001337892; NP_001337893
	NP_444352
	Wikidata
View/Edit Human	View/Edit Mouse

Inner mitochondrial membrane peptidase subunit 2 (IMMP2L) is an enzyme that in humans is encoded by the IMMP2L gene on chromosome 7. This protein catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the intermembrane space. IMMP2L processes the nuclear encoded protein DIABLO.