INHBA

INHBA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1NYS, 1NYU, 1S4Y, 2ARP, 2ARV, 2B0U, 2P6A, 3B4V, 4MID, 5HLY, 5HLZ
Identifiers
Aliases	INHBA, EDF, FRP, inhibin beta A, inhibin beta A subunit, inhibin subunit beta A
External IDs	OMIM: 147290; MGI: 96570; HomoloGene: 1653; GeneCards: INHBA; OMA:INHBA - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	41,705,834 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	16,206,206 bp
RNA expression pattern
	Top expressed in
	cartilage tissue; ; saphenous vein; ; vena cava; ; visceral pleura; ; stromal cell of endometrium; ; buccal mucosa cell; ; beta cell; ; placenta; ; caput epididymis; ; lower lobe of lung;
	Top expressed in
	cumulus cell; ; epithelium of lens; ; incisor; ; nasopharynx; ; ascending aorta; ; dental follicle; ; rib; ; efferent ductule; ; aortic valve; ; barrel cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transforming growth factor beta receptor binding; signaling receptor binding; hormone activity; identical protein binding; growth factor activity; cytokine activity; protein heterodimerization activity; type II activin receptor binding; peptide hormone binding; protein binding; inhibin binding;
Cellular component	inhibin A complex; activin A complex; perinuclear region of cytoplasm; extracellular region; extracellular space;
Biological process	negative regulation of cell population proliferation; eyelid development in camera-type eye; endodermal cell differentiation; negative regulation of follicle-stimulating hormone secretion; GABAergic neuron differentiation; cell-cell signaling; progesterone secretion; mesodermal cell differentiation; negative regulation of macrophage differentiation; odontogenesis; hair follicle development; hematopoietic progenitor cell differentiation; regulation of transcription by RNA polymerase II; negative regulation of phosphorylation; SMAD protein signal transduction; extrinsic apoptotic signaling pathway; positive regulation of follicle-stimulating hormone secretion; cell surface receptor signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; nervous system development; positive regulation of ovulation; positive regulation of gene expression; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; cellular response to cholesterol; mesoderm formation; activin receptor signaling pathway; negative regulation of B cell differentiation; ovarian follicle development; striatal medium spiny neuron differentiation; positive regulation of protein metabolic process; positive regulation of transcription, DNA-templated; hemoglobin biosynthetic process; roof of mouth development; positive regulation of erythrocyte differentiation; cellular response to follicle-stimulating hormone stimulus; regulation of MAPK cascade; cell development; positive regulation of transcription by RNA polymerase II; negative regulation of cell cycle; negative regulation of cell growth; cell differentiation; defense response; erythrocyte differentiation; male gonad development; regulation of follicle-stimulating hormone secretion; regulation of signaling receptor activity; G1/S transition of mitotic cell cycle; response to wounding; regulation of apoptotic process; negative regulation of hair follicle development; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	3624
	16323
	ENSG00000122641
	ENSMUSG00000041324
	P08476
	Q04998
	NM_002192
	NM_008380
	NP_002183; NP_002183.1
	NP_032406
	Wikidata
View/Edit Human	View/Edit Mouse

Inhibin, beta A, also known as INHBA, is a protein which in humans is encoded by the INHBA gene. INHBA is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.