INPP4A

INPP4A
Identifiers
Aliases	INPP4A, INPP4, TVAS1, inositol polyphosphate-4-phosphatase type I A
External IDs	OMIM: 600916; MGI: 1931123; HomoloGene: 2871; GeneCards: INPP4A; OMA:INPP4A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	98,594,392 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	37,449,817 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; endothelial cell; ; tibia; ; entorhinal cortex; ; postcentral gyrus; ; superior frontal gyrus; ; buccal mucosa cell; ; middle temporal gyrus; ; lateral nuclear group of thalamus; ; visceral pleura;
	Top expressed in
	perirhinal cortex; ; entorhinal cortex; ; CA3 field; ; trigeminal ganglion; ; primary visual cortex; ; superior frontal gyrus; ; granulocyte; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; Region I of hippocampus proper;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity; protein binding; hydrolase activity; inositol-3,4-bisphosphate 4-phosphatase activity; phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity; inositol-1,3,4-trisphosphate 4-phosphatase activity;
Cellular component	cytosol; cytoplasm;
Biological process	phosphatidylinositol biosynthetic process; phosphatidylinositol-3-phosphate biosynthetic process; inositol phosphate metabolic process; signal transduction; dephosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	3631
	269180
	ENSG00000040933
	ENSMUSG00000026113
	Q96PE3
	Q9EPW0
NM_001134224; NM_001134225; NM_001566; NM_004027; NM_001351424;
	NM_001351425; NM_001351426; NM_001351427; NM_001351428; NM_001351429
NM_001290797; NM_001290798; NM_001290799; NM_030266; NM_172971;
	NM_001374629; NM_001374630
NP_001127696; NP_001127697; NP_001557; NP_004018; NP_001338353;
	NP_001338354; NP_001338355; NP_001338356; NP_001338357; NP_001338358
NP_001277726; NP_001277727; NP_001277728; NP_084542; NP_766559;
	NP_001361558; NP_001361559
	Wikidata
View/Edit Human	View/Edit Mouse

Type I inositol-3,4-bisphosphate 4-phosphatase is an enzyme that in humans is encoded by the INPP4A gene.

INPP4A encodes the inositol polyphosphate 4-phosphatase type I, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate.