INPP5E

INPP5E
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XSW
Identifiers
Aliases	INPP5E, CORS1, CPD4, JBTS1, MORMS, PPI5PIV, inositol polyphosphate-5-phosphatase E, pharbin
External IDs	OMIM: 613037; MGI: 1927753; HomoloGene: 56863; GeneCards: INPP5E; OMA:INPP5E - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	136,439,845 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	26,299,215 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; secondary oocyte; ; right hemisphere of cerebellum; ; apex of heart; ; canal of the cervix; ; right lobe of thyroid gland; ; body of uterus; ; left ovary; ; right ovary; ; left lobe of thyroid gland;
	Top expressed in
	genital tubercle; ; spermatid; ; tail of embryo; ; granulocyte; ; cerebellar cortex; ; ventricular zone; ; aortic valve; ; cumulus cell; ; spermatocyte; ; ascending aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity; inositol-polyphosphate 5-phosphatase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; protein binding;
Cellular component	cytoplasm; cytosol; Golgi apparatus; cell projection; membrane; ruffle; Golgi membrane; plasma membrane; Golgi cisterna membrane; axoneme; cytoskeleton; cilium;
Biological process	phosphatidylinositol metabolic process; lipid metabolism; phosphatidylinositol dephosphorylation; phosphatidylinositol biosynthetic process; inositol phosphate dephosphorylation; biological process; negative regulation of protein localization to cilium;
	Sources:Amigo / QuickGO
Orthologs
	56623
	64436
	ENSG00000148384
	ENSMUSG00000026925
	Q9NRR6
	Q9JII1
	NM_019892; NM_001318502
	NM_001290437; NM_033134
	NP_001305431; NP_063945
	NP_001277366; NP_149125
	Wikidata
View/Edit Human	View/Edit Mouse

72 kDa inositol polyphosphate 5-phosphatase, also known as phosphatidylinositol-4,5-bisphosphate 5-phosphatase or Pharbin, is an enzyme that in humans is encoded by the INPP5E gene.