INPP5F

INPP5F
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4XUU
Identifiers
Aliases	INPP5F, MSTPO47, SAC2, hSAC2, MSTP007, inositol polyphosphate-5-phosphatase F
External IDs	OMIM: 609389; MGI: 2141867; HomoloGene: 8962; GeneCards: INPP5F; OMA:INPP5F - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	119,829,147 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	128,696,425 bp
RNA expression pattern
	Top expressed in
	Pons; ; superior vestibular nucleus; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; orbitofrontal cortex; ; pars compacta; ; middle temporal gyrus; ; ventral tegmental area; ; secondary oocyte; ; Region I of hippocampus proper;
	Top expressed in
	nucleus accumbens; ; pontine nuclei; ; lateral hypothalamus; ; dorsal tegmental nucleus; ; ventral tegmental area; ; globus pallidus; ; paraventricular nucleus of hypothalamus; ; dorsomedial hypothalamic nucleus; ; suprachiasmatic nucleus; ; Region I of hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	inositol monophosphate 1-phosphatase activity; inositol monophosphate phosphatase activity; protein homodimerization activity; inositol monophosphate 3-phosphatase activity; protein binding; phosphoric ester hydrolase activity; hydrolase activity; inositol monophosphate 4-phosphatase activity; phosphatidylinositol phosphate 4-phosphatase activity; phosphatidylinositol phosphate 5-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity;
Cellular component	dendrite; clathrin-coated pit; membrane; clathrin-coated endocytic vesicle; cytoplasm; early endosome membrane; endosome; recycling endosome; early endosome; axon; soma;
Biological process	phosphatidylinositol catabolic process; cardiac muscle hypertrophy in response to stress; regulation of protein kinase B signaling; phosphatidylinositol-mediated signaling; clathrin-dependent endocytosis; positive regulation of receptor recycling; phosphatidylinositol dephosphorylation; negative regulation of axon regeneration; phosphatidylinositol biosynthetic process; adult locomotory behavior; regulation of endocytic recycling; regulation of cell motility; negative regulation of peptidyl-serine phosphorylation; negative regulation of tyrosine phosphorylation of STAT protein;
	Sources:Amigo / QuickGO
Orthologs
	22876
	101490
	ENSG00000198825
	ENSMUSG00000042105
	Q9Y2H2
	Q8CDA1
	NM_001243194; NM_001243195; NM_014937
	NM_178641; NM_001346517
	NP_001230123; NP_001230124; NP_055752
	NP_001333446; NP_848756
	Wikidata
View/Edit Human	View/Edit Mouse

Inositol polyphosphate-5-phosphatase F is a protein that in humans is encoded by the INPP5F gene.