INSM1

INSM1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2LV2, 3ZMS
Identifiers
Aliases	INSM1, IA-1, IA1, INSM transcriptional repressor 1
External IDs	OMIM: 600010; MGI: 1859980; HomoloGene: 31080; GeneCards: INSM1; OMA:INSM1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	20,370,949 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	146,066,940 bp
RNA expression pattern
	Top expressed in
	beta cell; ; ganglionic eminence; ; ventricular zone; ; pituitary gland; ; anterior pituitary; ; cerebellar vermis; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; paraflocculus of cerebellum; ; putamen;
	Top expressed in
	medial ganglionic eminence; ; Rostral migratory stream; ; pineal gland; ; ventricular zone; ; islet of Langerhans; ; fossa; ; lumbar spinal ganglion; ; trigeminal ganglion; ; olfactory system; ; olfactory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; histone deacetylase binding; metal ion binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; nucleic acid binding; chromatin DNA binding; cyclin binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription repressor complex; nucleoplasm; nucleus;
Biological process	sympathetic ganglion development; negative regulation of protein phosphorylation; noradrenergic neuron development; cell differentiation; regulation of transcription, DNA-templated; norepinephrine biosynthetic process; positive regulation of cell migration; pancreatic A cell differentiation; negative regulation of transcription by RNA polymerase II; nervous system development; transcription, DNA-templated; multicellular organism development; positive regulation of neural precursor cell proliferation; adrenal chromaffin cell differentiation; endocrine system development; positive regulation of cell differentiation; positive regulation of cell population proliferation; regulation of gene expression; cell cycle; type B pancreatic cell development; regulation of protein-containing complex assembly; type B pancreatic cell differentiation; endocrine pancreas development; negative regulation of cell population proliferation; transdifferentiation; regulation of cell cycle process; neuron differentiation;
	Sources:Amigo / QuickGO
Orthologs
	3642
	53626
	ENSG00000173404
	ENSMUSG00000068154
	Q01101
	Q63ZV0
	NM_002196
	NM_016889
	NP_002187
	NP_058585
	Wikidata
View/Edit Human	View/Edit Mouse

Insulinoma-associated protein 1 is a protein that in humans is encoded by the INSM1 gene.