IQGAP2

IQGAP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IEZ, 4EZA
Identifiers
Aliases	IQGAP2, IQ motif containing GTPase activating protein 2
External IDs	OMIM: 605401; MGI: 2449975; HomoloGene: 101543; GeneCards: IQGAP2; OMA:IQGAP2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	76,708,132 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	96,028,991 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; ventricular zone; ; glomerulus; ; metanephric glomerulus; ; secondary oocyte; ; liver; ; right lobe of liver; ; duodenum; ; parotid gland; ; monocyte;
	Top expressed in
	ciliary body; ; retinal pigment epithelium; ; parotid gland; ; iris; ; left lobe of liver; ; epithelium of stomach; ; submandibular gland; ; left colon; ; jejunum; ; lacrimal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	Arp2/3 complex binding; GTPase inhibitor activity; actin filament binding; actin binding; phosphatidylinositol-3,4,5-trisphosphate binding; calmodulin binding;
Cellular component	cytoplasm; filamentous actin; cytosol; filopodium; microvillus; cell surface; actin cytoskeleton; microtubule; extracellular exosome; lamellipodium; plasma membrane; secretory granule membrane;
Biological process	thrombin-activated receptor signaling pathway; regulation of GTPase activity; Arp2/3 complex-mediated actin nucleation; signal transduction; negative regulation of GTPase activity; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	10788
	544963
	ENSG00000145703
	ENSMUSG00000021676
	Q13576
	Q3UQ44
	NM_001285460; NM_001285461; NM_001285462; NM_006633
	NM_027711
	NP_001272389; NP_001272390; NP_001272391; NP_006624
	NP_081987
	Wikidata
View/Edit Human	View/Edit Mouse

Ras GTPase-activating-like protein IQGAP2 is an enzyme that in humans is encoded by the IQGAP2 gene.