IRF2

IRF2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1IRF, 1IRG, 2IRF
Identifiers
Aliases	IRF2, IRF-2, interferon regulatory factor 2
External IDs	OMIM: 147576; MGI: 96591; HomoloGene: 1659; GeneCards: IRF2; OMA:IRF2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	184,474,558 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	47,300,493 bp
RNA expression pattern
	Top expressed in
	monocyte; ; blood; ; Achilles tendon; ; granulocyte; ; olfactory zone of nasal mucosa; ; appendix; ; spleen; ; lymph node; ; rectum; ; right adrenal cortex;
	Top expressed in
	granulocyte; ; blood; ; left colon; ; spleen; ; left lobe of liver; ; mesenteric lymph nodes; ; muscle of thigh; ; thymus; ; duodenum; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; focal adhesion; nucleoplasm; cytosol;
Biological process	interferon-gamma-mediated signaling pathway; cell population proliferation; blood coagulation; regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; type I interferon signaling pathway; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; immune system process;
	Sources:Amigo / QuickGO
Orthologs
	3660
	16363
	ENSG00000168310
	ENSMUSG00000031627
	P14316
	P23906
	NM_002199
	NM_008391
	NP_002190
	NP_032417
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.